翻訳と辞書 Words near each other ・ Lysurus pakistanicus ・ Lysurus periphragmoides ・ Lysus ・ Lysva ・ Lysva River ・ Lysvaella ・ Lysvatnet ・ Lysvatnet (Lenvik) ・ Lysvatnet (Meløy) ・ Lysvik ・ Lysychansk ・ Lysychnyky ・ Lysye Gory ・ Lysyl endopeptidase ・ Lysyl hydroxylase ・ Lysyl oxidase ・ Lysyltransferase ・ Lysá hora ・ Lysá nad Labem ・ Lysá pod Makytou ・ Lysøen ・ Lysøysundet ・ Lyta Alexander ・ Lytavry ・ Lytchett Bay ・ Lytchett Heath ・ Lytchett karting league ・ Lytchett Matravers ・ Lytchett Minster ・ Lytchett Minster and Upton Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Lysyl oxidase ： ウィキペディア英語版 Lysyl oxidase Lysyl oxidase (LOX), also known as protein-lysine 6-oxidase, is a protein that, in humans, is encoded by the ''LOX'' gene.〔(【引用サイトリンク】 url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=4015 )〕 Its inhibition can cause osteolathyrism, but, at the same time, its upregulation by tumor cells may promote metastasis of the existing tumor, causing it to become malignant and cancerous. == Structure == In the yeast strain ''Pichia pastoris'', lysyl oxidase constitutes a homodimeric structure. Each monomer consists of an active site that includes a Cu(II) atom coordinated with three histidine residues as well as 2,4,5-trihydroxyphenalanine quinone (TPQ), a crucial cofactor. In humans, the LOX gene is located on chromosome 5q23.3-31.2. The DNA sequence encodes a polypeptide of 417 amino acids, the first 21 residues of which constitute a signal peptide,〔 with a weight of approximately 32 kDa. The carboxyterminus contains the active copper (II) ion, lysine, tyrosine, and cysteine residues that comprise the catalytically active site. The three-dimensional structure of human lysyl oxidase has not yet been resolved. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Lysyl oxidase」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.